I. Project Name

Shanghai Huang Pharmaceutical Co., Ltd. Clock Server ( NTP ) Project deployment (covering full‑scene time synchronization across the formulation production workshop, the quality inspection center, and the warehouse management system)

II. Duration of Cooperation

2026  Year One Quarterly (covering the entire lifecycle, including requirements gathering, solution design, installation and commissioning, and acceptance testing)

• Company Overview

Beijing Zhongxinchuang Technology Co., Ltd. was established in 2002 Founded in [year], the company is headquartered in Beijing’s Zhongguancun Software Park and is a leading high-tech enterprise in China’s time‑frequency synchronization sector, with deep expertise in the research, development, and application of time synchronization technologies. 22 year. The company has established four major technical systems—fully digital phase-locked loops, proactive leap-second handling, operations-and-maintenance encryption, and adaptation of domestically produced core components—and has cumulatively obtained 11 A software copyright registration certificate, a software product registration certificate, and several utility model patents have been obtained, thereby… ISO9001 Authoritative certifications, including the Quality Management System, National High-Tech Enterprise, and Zhongguancun High-Tech Enterprise.

The company’s product portfolio encompasses four major series: time synchronization devices, remote power controllers, data acquisition units, and serial-to-Ethernet converters. 80 For the remaining products, customized solutions are available, with business coverage spanning government, finance, healthcare, energy, rail transit, pharmaceuticals, and defense industries. 20 more than industries, serving over global customers 1973 Home. Leveraging its technological expertise, it has provided timing services for the return‑to‑Earth imaging of the Shenzhou‑14 manned spacecraft and for the Beijing Olympic subway system. 8 Line, National High-Speed Rail 5G Provides time synchronization assurance for critical scenarios such as base stations and Peking Union Medical College Hospital; core product. DNTS The series has achieved full domestic production of its core components and can be optionally equipped with Hygon processors. C86 Information Technology Innovation Platform, Changxin / Domestic components such as Ziguang memory and Yangtze Memory hard drives meet the requirements for independent and controllable solutions in critical sectors.

IV. Purchased Products

NTP Network Time Server (Model: DNTS-9 S , multifunctional)

• Key specifications: GPS / Beidou / GLONASS/Galileo Multi-system compatible receiver, temperature-compensated crystal oscillator timing unit
• Network specifications: 4 RJ-45 Gigabit Ethernet port, supports IPv4/IPv6 Dual-stack and 10-Gigabit Ethernet port expansion
• Security Features: Supported RSA Asymmetric encryption, MD5/SHA/AES/DES/RC4 Encryption and authentication, compliant with the Level 3 requirements of the Cybersecurity Classified Protection Scheme.

V. Customer Requirements

1. Compliance Requirements: Strictly Compliant with the Pharmaceutical Industry GMP Certification and FDA 21 CFR Part 11 Electronic record and electronic signature standards ensure that timestamps throughout the entire process—covering production process parameters, inspection data, and warehouse logistics—are authentic and traceable, with timestamp accuracy meeting minute-level requirements and network system synchronization errors kept within… 5 Within seconds;
2. Full-scenario synchronization requirement: Implement in the formulation workshop. 3 production line PLC Control System, Quality Inspection Center 28 Taiwanese precision analytical instruments (including liquid chromatographs, gas chromatographs, etc.), laboratory LIMS System, warehousing WMS System and 15 The time across the server cluster must be synchronized with millisecond-level precision to ensure the accuracy of cross-system data correlation.
3. Redundancy and reliability requirements: Possess GPS / Beidou dual-satellite source + Built-in timing unit with redundant backup capability addresses satellite signal interruptions caused by the shielding environment in workshops, ensuring continued operation even when the primary time source fails. ≥72 High-precision time synchronization by the hour;
4. Management and O&M requirements: Supported Web/SNMP/SSH Multi‑mode remote monitoring allows you to view device operating status, satellite signal strength, and client synchronization status in real time, while automatically generating and storing synchronization logs. ≥3 Year, support for exception email / SMS alert;
5. Environmental adaptation requirements: The equipment must be suitable for pharmaceutical cleanrooms. Class D Class‑clean environment, featuring electromagnetic interference resistance, dust protection, and low noise, with an operating temperature range that covers… 10℃~30℃ , meeting industrial-grade continuous-operation standards.

VI. Solution

1. Core Equipment Deployment:
   • Configuration 1 Taiwan DNTS-9 Multi-functional NTP The servers are organized into an active‑standby cluster, all equipped with 72 Multi-system receiver for channels (tracking sensitivity) - 166 dBm ), supports customizable satellite signal priority to ensure stable signal reception in complex workshop environments;
   • Standard configuration includes a temperature-compensated crystal oscillator timing unit (timing accuracy better than 8.6us/day ), optionally equipped with a domestically produced aerospace-grade rubidium atomic clock (with timing accuracy better than 500ns/day ), meeting the high-precision timekeeping requirements in scenarios where satellite signals are unavailable for extended periods;
   • Device interface expansion: Equipped with 4 road USB 2.0/3.0 Interface (for log backup and system upgrade), 2 road RS232 Console Interface, 1 road TOD Time output interface ( RS232/RS485 Level), meeting the communication requirements of various industrial devices in the workshop.

1. Redundant Architecture Design:
   • Adopting a dual-receiver configuration + Dual-antenna physical isolation deployment: the antennas are mounted on rooftops facing different orientations within the plant area to prevent simultaneous shadowing.
   • Enable NTP Peer In mutual backup mode, the primary and standby servers synchronize their status in real time. When the primary server loses signal or experiences a failure, it automatically switches over to the standby server, with a switchover time of… ≤3 seconds, ensuring the continuity of time synchronization;
   • Equipped with 1+1 Hot‑redundant dual power supplies (supporting hot swapping), utilizing Great Wall‑made domestic power modules, MTBF (Mean Time Between Failures) reaches 90000 Hours, meeting industrial-grade high-reliability requirements.

1. Security and Compliance Assurance:
   • Deploy a tiered user permission management system, establishing three levels of permissions—administrator, operations and maintenance personnel, and auditor—and requiring two-factor authentication for critical operations, in compliance with… FDA 21 CFR Part 11 Compliance requirements for electronic signatures;
   • The logging system supports audit trails, recording all device configuration changes, synchronization requests, and alarm events, including key information such as the operator, operation time, and operation details. The log format complies with… GMP Audit requirements: support export. PDF/Excel Format archive.

1. Management Platform Deployment:
   • Installation DNTS Manager Centralized monitoring software that supports simultaneous management. 2 Taiwan server and 100 + Client devices provide a visual display of key metrics such as the number of tracked satellites, synchronization accuracy, and network load.
   • Configure a multi-dimensional alert mechanism that, when satellite signals are lost, synchronization accuracy exceeds the threshold, or equipment malfunctions, triggers alerts via... syslog/email Dual-push alert notifications, alert response time ≤5 minutes;
   • Supports custom time synchronization policies, allowing you to configure synchronization intervals by workshop and equipment type. 1-30 (adjustable in minutes), and for precision instruments, set the high-frequency synchronization mode ( 1 minute / Next time).

1. Customized Implementation Services:
   • Preliminary Research: Conducted in collaboration with the client’s technical team. 3 Conduct on-site inspections and organize/clarify. 12 Class common 107 The Taiwan side must align the interface types, network topology, and installation environment requirements of the equipment.
   • Installation and Commissioning: Dedicated cleanroom installation tools are used, and equipment placement is optimized to avoid process piping and sources of electromagnetic interference. Antenna cables are shielded and routed through conduits for protection, in compliance with cleanroom construction standards.
   • Training and Delivery: Conducting 2 On-site specialized training (operational training) + Emergency response training), providing a comprehensive technical documentation package that includes equipment manuals, calibration reports, and compliance verification reports to assist customers in completing… GMP Compliance filing.
   • 

VII. Implementation Outcomes

1. Time synchronization accuracy meets the standard:
   • Entire plant area 107 Terminal devices achieve time synchronization, with the synchronization error within the local area network remaining stable at 0.03-2ms , Synchronization error of precision analytical instruments ≤0.5ms ， 1PPS Signals and UTC Master clock synchronization accuracy ≤5ns , far superior to GMP and FDA 21 CFR Part 11 Required time accuracy standard;
   • In the event of satellite signal loss, the built-in temperature-compensated crystal oscillator maintains timekeeping. 60 Hours later, time drifts. ≤30us , meeting the continuous timing requirements of critical production processes.

1. System Stability Verification:
   • Equipment trial operation 3 Within the month, there were no instances of timing service interruptions, signal loss, or malfunctions, and the redundant switchover success rate was… 100% , environmental adaptability is achieved through 10℃~30℃ Verification of the cleanroom’s actual operation; electromagnetic compatibility testing complies with… GB/T 17626 Standard;
   • The server processes an average of synchronization requests per day. ≥8000 Next, CPU Load ≤30% , network bandwidth usage ≤5Mbps , with no performance bottlenecks.

1. Significant improvement in management efficiency:
   • Enables visualized, centralized management of the timing system, reducing manual maintenance workload. 70% , the time required for verifying synchronization status has been reduced from the original manual, unit-by-unit inspection to... 4 hour / Next, it has been shortened to a one-click verification on the platform. 5 minute / Next;
   • The automatic log retention period reaches 5 Year, satisfy GMP Regarding the long-term preservation requirements for data traceability, the audit preparation time has been reduced from… 15 The day is shortened to 3 Heaven, significantly enhancing compliance audit efficiency.

1. Comprehensive compliance fulfillment:
   • Helping customers pass smoothly 2024 Annual GMP During the re‑review, the time‑traceability system was verified to be free of issues, and the relevant technical documentation has been incorporated into the customer’s compliance management template.
   • The system is fully compliant with the Level 3 technical specifications of the “Basic Requirements for Cybersecurity Classified Protection” and FDA 21 CFR Part 11 Electronic record‑keeping and electronic signature requirements provide time‑synchronization compliance support for customers’ products exported to the European and U.S. markets.

VIII. Application Cases

Shenzhen: Huawei, ZTE, Datang, Honeywell (China), Yokogawa Electric (China), Emerson (China) Motors, Nokia, Siemens (China), ABB China, Schneider Electric (China), Baidu, Alibaba Cloud, Tencent Cloud, Zhejiang Dahua Group, Sail Network, Beijing Banknote Printing, Jinnan Data Lake, Visionox, Qingdao Hisense Network, Fujian Newland Software Engineering, Beijing HuaSheng TianCheng, Fujian Rongji Software Co., Ltd., Shanghai BaoXin Software Co., Ltd., Shanghai Tianbai Broadband Network, China Tobacco (Yunnan) Reconstituted Tobacco Leaf, Chongqing Cigarette Factory, Shengle Industrial Park, Beijing Shouchuang Environmental Protection Group, BOE, Lenzing (Nanjing) Fibers, Digital China (China), Tsinghua Unigroup, Shanghai Bell, Taiwan’s Formosa Plastics, Weihai Triangle Tire, Henan Huayuan Photovoltaic, Jiaxing Duoneng Automation Equipment, Tangshan Sanyou Chlor-Alkali Company, Inner Mongolia Desheng Blast Furnace Overhaul Project, Winosin, Shanghai Tieda Telecom, Nanjing EnruiTe Industrial, Jinchang Construction, AVIC Engineering Integrated Equipment, Hangzhou Enhé Bio, Shandong Fangxin Network, Beijing Xuedilong, Lunan Pharmaceutical Group (pharmaceutical industry), Guangzhou Jianxin, Hou Niwei'er, Tianyi Cloud, SMIC South, Jiaxing Huashu, Chengdu Guowei Biopharmaceuticals (pharmaceutical industry), Aerospace 8 Institute, Sichuan Guowei Pharmaceutical (pharmaceutical industry), Dongying Yellow River Delta Digital Exhibition Hall Project, Rockwell, Xiaoshan ENN Smart Operations Center, Erxianmiao Security Project, France SPL Cement project, FAW Dongji Gong shock absorbers, Shanghai SMIC Oriental, Emerson Process Control, Adisseo Nanjing, Chongqing Lottery, INEOS Styrenics polymer materials ( Ningbo ) Jiangsu Shituo, Juguang Technology, Guangzhou Cigarette Factory, Chongqing Xingwang, Beijing Mining & Metallurgy Science & Technology Group, Digital Ningxia Construction & Operation, Xinxu Group, Xinjiang Xinye, BOE Huacan Optoelectronics Zhejiang, Hangzhou Holley Automation, Beijing Tiantan Biological Products (pharmaceutical industry), China United Network Communications Pingdingshan Branch, Laos BRT Shandong Qisheng Industry and Trade Co., Ltd., Zhuzhou CRRC Semiconductor, Anhui Huasu Co., Ltd., Fujian Haiquan Chemical, Chongqing BOE Optoelectronics Technology, ASE Enterprise Services (Shanghai), SMIC, and others.